OT: - What changes are you and family making to your lifestyle due to coranavirus? | Page 47 | The Boneyard

OT: What changes are you and family making to your lifestyle due to coranavirus?

Palatine said:
Gilead is saying this morning that two-thirds of the patients in their "remdesivir" trial improved with the drug. It had previous been used to treat Ebola. Very small sample size under 60 patients.
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Emory University is conducting a study on remdesivir. It's a double blind study (the largest in the world for this drug) with results to be reported in about a week. The head of the study does not know who received a placebo and who received remdesivir but he stated that a number of patients have a reduction in the duration of infection. It's obvious he believes those patients are getting remdesivir even if he can't state it. If these people have antibodies against the virus then we have a treatment for at least some portion of the population.

AZHuskiePop said:
There 50 companies with alleged cures all just waiting for millions from the US government to move forward and you expect a cheap generic drug to be accepted by the medical establishment That would be like killing the goose who lays golden eggs.
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Brazil just discontinued a study on Hydroxychloroquine/Azithromycin after concluding there is no benefit to patients. Some people in the Emory hospital are refusing to partake in the trial insisting on the antimalarial modality of treatment. I'll wait for the studies conducted by WHO and the CDC to determine if the antimalarial treatment is effective or not. Humanity is desperate for something but these medicines are not absolutely safe. If they are indeed ineffective we could be killing an equal percentage of people with indiscriminate usage of the antimalarial medications as the Coronid-19 virus.

In the best of times there are problems with medications and not all of those problems were the result of graft. Under current conditions we can expect hysteria to increase the chances of problems. That certainly doesn't mean that everyone pursuing a treatment is corrupt. There is validity behind the majority of the scientific communities reluctance to give the green light to any of these proposed solutions without at least some study. The compromise is the choice to allow promising studies to fast track without further studies to determine if the treatment is worse than the disease.
 
Jaker said:
Changes I am making in my portfolio, buying up biomedicals, like Abbott labs- 5 minute CV19 test and Pfizer who is working on the vaccine.
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Look into Gilead. Right now remdesivir is compassionate use but if it’s approved and this is long-term, this could be a good buy.
 
8893 said:
Two of my daughters had their birthdays during this craziness already and I was in the same boat. I usually spend a lot of time searching for the perfect card, so this year I decided to take that time to write each of them a heartfelt message instead, which included my memory of the day each of them was born and my take on what makes each of them special. It was therapeutic for me, and each of them really seemed to appreciate it--or at least I took the tears as a good sign!

It was the 21st birthday for one of them and she was bummed not to be celebrating with her friends at school as planned. We made a party of it though and surprised her by turning our kitchen and common room into a makeshift nightclub and bar, complete with strobe lights, shots, thump-thump music...and a massive hangover.

In any event, happy birthday to him. Mine is on Tuesday and I still remember the one year it fell on Easter, when I was eight or nine years old. My favorite aunt got me an enormous chocolate bar that was made in the image of The Last Supper. To this day I remember it as one of the coolest gifts I ever got. I ate that thing for more than a week, breaking off a different apostle each day, and saving Jesus for last, of course.
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Happy Birthday 88 hope you have a great day, considering the current events.
 
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browndog319 said:
Look into Gilead. Right now remdesivir is compassionate use but if it’s approved and this is long-term, this could be a good buy.
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I've held Gilead for over a month, it hasn't done anything.
 
NJHusky said:
Unlike the rest of the economy??
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Are you being intentionally obtuse?

You asked why the hospitals are asking for the feds to help with supplies. Their revenues have been drastically slashed, they are the very definition of essential services, and they have to make payroll, procure supplies, and continue to operate.

Are you living in an alternate reality where only the hospitals have asked the Federal and/or State government for help?
 
How long will our food supply (meats/vegetables) last without higher prices or even worse, shortages?

I know short term we're ok, but this could become a big issue.

I'm considering buying a freezer, and my wife is actually frightened. Hell she is even buying spam and other canned meat now. I wished she would stay away from the TV (i.e. news).

 
Kitaman said:
How long will our food supply (meats/vegetables) last without higher prices or even worse, shortages?

I know short term we're ok, but this could become a big issue.

I'm considering buying a freezer, and my wife is actually frightened. Hell she is even buying spam and other canned meat now. I wished she would stay away from the TV (i.e. news).

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Check out the garden thread. Some good advice.
 
Palatine said:
It's not misleading at all. It is simply matching apples to apples for the purpose of drawing a comparison and everything is labeled. The conversation was about whether the non-corona death rate had risen. It hasn't.

The March numbers are the March numbers. You are trying to make something political that is not political at all. In fact, I can not tell what you are trying to say at all.

Do you have a point?
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apple.news

There’s Been a Spike in People Dying at Home in Several Cities. That Suggests Coronavirus Deaths Are Higher Than Reported. — ProPublica

Coronavirus death counts are based on positive tests and driven by hospital deaths. But data from major metropolitan areas shows a spike in at-home deaths, prompting one expert to say current numbers were just “the tip of the iceberg.”
apple.news apple.news
 
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The old folks in the USA aren't the ones threatened as once thought. This is sobering info.


EVliZF0WAAYAAom
 
Dream Jobbed 2.0 said:
More and more outlets (including the Today Show) have picked up on the meat shortage news. Even if there’s no meat shortage there will be
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They are going to start another (probably needless) run. The news needs ratings and the worst case scenario draws more eyeballs than likely scenarios. Discriminating people understand what is news and what is for effect but also need to keep an eye on the Chicken Littles' reactions.
 
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Husky25 said:
They are going to start another (probably needless) run. The news needs ratings and the worst case scenario draws more eyeballs than likely scenarios. Discriminating people understand what is news and what is for effect but also need to keep an eye on the Chicken Littles' reactions.
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Yeah I posted the news story above because my wife is one of those people (chicken littles). The Her word of mouth is equally effective as Twitter. That's how this stuff spreads with uniformed statements, no facts and no research.
 
In experimental treatments, Connecticut hospitals are using blood plasma from recovered coronavirus patients to help those who are still sick

Medical professionals are beginning trials and experimental treatments that involve taking blood plasma — which is the fluid component of blood — from recovered coronavirus patients and infusing it into the bloodstreams of severely ill patients. The plasma from the recovered patients contains antibodies, which help the human body fight pathogens such as bacteria and viruses.

While still unproven on a large scale, the theory is that a recovered COVID-19 patient’s antibodies should also help fight the disease in patients who are still sick.

“If you can take that same plasma and infuse it into a patient that’s in the ICU or really compromised, you can fight the infection with the antibodies from the [plasma],” said Dr. Justin Lundbye, chief medical officer at Waterbury Hospital. “Those antibodies will then go after the virus and kill it.”

Trinity Health was the first hospital system with Connecticut locations to begin a clinical trial using the plasma therapy, although Yale New Haven Health is applying for approval of a trial. The Yale New Haven Health, Nuvance Health and Hartford HealthCare systems are also using blood plasma in a more traditional, non-trial setting.

A number of hospitals across the state, including the Hartford HealthCare and Yale New Haven Health systems, are gearing up to provide convalescent plasma transfusions outside of the scope of a clinical trial, in a less rigorous program that the FDA refers to as “expanded access.” (In the meantime, Yale New Haven Health is also applying to conduct its own clinical trial.)

Although medical professionals around the world are now studying convalescent plasma, they have not yet proven whether it’s effective in treating COVID-19.

However, both Hussain, of Trinity Health, and Dr. Mahalia Desruisseaux of Yale New Haven Health pointed to promising results out of a small Chinese study of five critically ill COVID-19 patients. In that study, three of the patients were released from the hospital and two were stabilized after convalescent plasma treatment.

Another Chinese study showed similar results but was again very small, with only 10 patients.

Hussain also pointed to the track record of convalescent plasma in fighting other viral epidemics, from before COVID-19 came on the scene. When treated with convalescent plasma, patients had a better chance of beating Ebola, H1N1 and SARS, previous studies have found.

Trinity Health was one of the first four health systems in the U.S. to gain approval for a clinical trial of convalescent plasma. The health system has hospitals across Connecticut and Massachusetts, including St. Francis Hospital and Medical Center in Hartford and Mercy Medical Center in Springfield.

Hussain said the health system rushed to apply for a clinical trial after reading about the five-patient study in China. The study was small and didn’t have a comparison group, but Hussain said the results were attention-grabbing nonetheless.

“It’s amazing that [three patients] were able to go home,” Hussain said. “We thought, ‘We need to look into this and see what we can give our patients.’ ”

The hospital system is already using other treatments, such as hydroxychloroquine, for moderately ill patients, but there currently is no viable treatment for severely ill patients, Hussain said. So Trinity Health decided to target severely ill patients with the convalescent plasma trial.

“There isn’t really anything out there that we’re using for severe disease," Hussain said.

Dr. Latha Dulipsingh of St. Francis said on Thursday that the Trinity Health system hopes to give the first convalescent plasma transfusion by late this week. Dulipsingh said the hospital system will share results once it has enrolled 10 to 15 patients.

But Hussain said the health system will enroll as many patients as possible, in order to strengthen the study’s statistical analysis. He estimated the health system should be able to release data in about a month. The study will focus mainly on whether the treatment increases patients’ chances of survival.

“The primary outcome definitely is mortality,” Hussain said. “We want to make sure we’re able to save these patients.”

In lieu of clinical trials, some hospitals are using convalescent plasma under a protocol that the FDA dubs “expanded access." This approach, more similar to the typical in-patient treatment process, does not come with many of the requirements of a more formal clinical trial and is designed for patients who cannot participate in trials.

Under the expanded access protocol, only the most severely ill COVID-19 patients can be treated with convalescent plasma. Desruisseaux, at Yale New Haven Health, said some patients who are not yet critically ill may also be treated, if their doctors determine that they will soon become critically ill.

The Hartford HealthCare, Nuvance Health and Yale New Haven Health systems are gearing up to administer convalescent plasma under this protocol. The systems are receiving blood plasma from partner blood centers, such as the Rhode Island Blood Center and the American Red Cross.

The Yale New Haven Health system was scheduled to receive its first convalescent plasma unit on Tuesday morning, according to Tormey. Nuvance Health, which includes Danbury and Norwalk hospitals, has said it is recruiting a program that will start later this month. And Hartford HealthCare’s Dr. Ajay Kumar said the convalescent plasma program has not yet started in the hospital system, but “will begin as soon as we identify the patients.”
 
jostar1 said:
In experimental treatments, Connecticut hospitals are using blood plasma from recovered coronavirus patients to help those who are still sick

Medical professionals are beginning trials and experimental treatments that involve taking blood plasma — which is the fluid component of blood — from recovered coronavirus patients and infusing it into the bloodstreams of severely ill patients. The plasma from the recovered patients contains antibodies, which help the human body fight pathogens such as bacteria and viruses.

While still unproven on a large scale, the theory is that a recovered COVID-19 patient’s antibodies should also help fight the disease in patients who are still sick.

“If you can take that same plasma and infuse it into a patient that’s in the ICU or really compromised, you can fight the infection with the antibodies from the [plasma],” said Dr. Justin Lundbye, chief medical officer at Waterbury Hospital. “Those antibodies will then go after the virus and kill it.”

Trinity Health was the first hospital system with Connecticut locations to begin a clinical trial using the plasma therapy, although Yale New Haven Health is applying for approval of a trial. The Yale New Haven Health, Nuvance Health and Hartford HealthCare systems are also using blood plasma in a more traditional, non-trial setting.

A number of hospitals across the state, including the Hartford HealthCare and Yale New Haven Health systems, are gearing up to provide convalescent plasma transfusions outside of the scope of a clinical trial, in a less rigorous program that the FDA refers to as “expanded access.” (In the meantime, Yale New Haven Health is also applying to conduct its own clinical trial.)

Although medical professionals around the world are now studying convalescent plasma, they have not yet proven whether it’s effective in treating COVID-19.

However, both Hussain, of Trinity Health, and Dr. Mahalia Desruisseaux of Yale New Haven Health pointed to promising results out of a small Chinese study of five critically ill COVID-19 patients. In that study, three of the patients were released from the hospital and two were stabilized after convalescent plasma treatment.

Another Chinese study showed similar results but was again very small, with only 10 patients.

Hussain also pointed to the track record of convalescent plasma in fighting other viral epidemics, from before COVID-19 came on the scene. When treated with convalescent plasma, patients had a better chance of beating Ebola, H1N1 and SARS, previous studies have found.

Trinity Health was one of the first four health systems in the U.S. to gain approval for a clinical trial of convalescent plasma. The health system has hospitals across Connecticut and Massachusetts, including St. Francis Hospital and Medical Center in Hartford and Mercy Medical Center in Springfield.

Hussain said the health system rushed to apply for a clinical trial after reading about the five-patient study in China. The study was small and didn’t have a comparison group, but Hussain said the results were attention-grabbing nonetheless.

“It’s amazing that [three patients] were able to go home,” Hussain said. “We thought, ‘We need to look into this and see what we can give our patients.’ ”

The hospital system is already using other treatments, such as hydroxychloroquine, for moderately ill patients, but there currently is no viable treatment for severely ill patients, Hussain said. So Trinity Health decided to target severely ill patients with the convalescent plasma trial.

“There isn’t really anything out there that we’re using for severe disease," Hussain said.

Dr. Latha Dulipsingh of St. Francis said on Thursday that the Trinity Health system hopes to give the first convalescent plasma transfusion by late this week. Dulipsingh said the hospital system will share results once it has enrolled 10 to 15 patients.

But Hussain said the health system will enroll as many patients as possible, in order to strengthen the study’s statistical analysis. He estimated the health system should be able to release data in about a month. The study will focus mainly on whether the treatment increases patients’ chances of survival.

“The primary outcome definitely is mortality,” Hussain said. “We want to make sure we’re able to save these patients.”

In lieu of clinical trials, some hospitals are using convalescent plasma under a protocol that the FDA dubs “expanded access." This approach, more similar to the typical in-patient treatment process, does not come with many of the requirements of a more formal clinical trial and is designed for patients who cannot participate in trials.

Under the expanded access protocol, only the most severely ill COVID-19 patients can be treated with convalescent plasma. Desruisseaux, at Yale New Haven Health, said some patients who are not yet critically ill may also be treated, if their doctors determine that they will soon become critically ill.

The Hartford HealthCare, Nuvance Health and Yale New Haven Health systems are gearing up to administer convalescent plasma under this protocol. The systems are receiving blood plasma from partner blood centers, such as the Rhode Island Blood Center and the American Red Cross.

The Yale New Haven Health system was scheduled to receive its first convalescent plasma unit on Tuesday morning, according to Tormey. Nuvance Health, which includes Danbury and Norwalk hospitals, has said it is recruiting a program that will start later this month. And Hartford HealthCare’s Dr. Ajay Kumar said the convalescent plasma program has not yet started in the hospital system, but “will begin as soon as we identify the patients.”
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What does dude of WV think of this? ;-)
 
Update on my 4th living room setup of the month: my wife is currently saying “it’s really cold in here today!” Which is why I told her we didn’t want to move the couch to in front of the HVAC vent to which she said “I don’t think that will matter.”
 
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Palatine said:
Youngsters may be threatened for hospitalization but much less so for death.
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But have they put a number on the decreased life expectancy that comes with a bout of the virus? And will the damage be classified a "pre-existing condition"?
 
Waquoit said:
But have they put a number on the decreased life expectancy that comes with a bout of the virus? And will the damage be classified a "pre-existing condition"?
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Not that I am aware of. I think you need a longitudinal study to come up with real life expectancy numbers. Hard to say if there will be any long term effect among the young but it seems unlikely unless significant damage is done to the lungs and those would be ICU type cases.
 
Palatine said:
Not that I am aware of. I think you need a longitudinal study to come up with real life expectancy numbers. Hard to say if there will be any long term effect among the young but it seems unlikely unless significant damage is done to the lungs and those would be ICU type cases.
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Still early but...
 
Palatine said:
Youngsters may be threatened for hospitalization but much less so for death.View attachment 53114
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In Massachusetts, as of yesterday 995 people dead. Of those 444 were residents in long term care/nursing home facilities.

It clearly affects some younger people, but the odds for those people are reasonably good.
 
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