When the NCAA awarded a regional to Portland, OR for 2 consecutive years (or was it 3 years?), it was with the assumption that either Oregon or Oregon State would be good enough to be a Top 16 seed and bring a lot of fans to the regional. Don't kid yourselves to think that Oregon is going to be sent to any regional other than Portland, regardless of whether they are a #1 or #2 seed.
Stanford is deserving of a #1 seed, IMO, over Oregon, and they have a proximity argument as to being sent to Portland instead of the Ducks. But, would attendance be even close with Stanford there instead of Oregon? I don't think so.
Same premise as when the committee awards Regionals to cities in the northeast -- because UConn fans will buy tickets and support their team year in and year out.