actually the Louisville weakside DE stunted underneath, and the tackle was going straight up field and got off the block to set the edge, Abernathy was still isolated 1-1 with a single defender to beat (as long as the other 9 maintained blocks) and made a move and ran right around the defender and straight to the endzone untouched.
You need all your players to make their blocks on the field for the running game to work well, and you also need a ball carrier, that the vast majority of the time, is going to have to either make somebody miss, or run through and over somebody to get big chunks of yardage.