I think the key to the game is the Pats offensive line. If they can protect Brady well, I feel good about the Pats chances.
Also, Brady is the best football player of all time in my opinion. He has won 5 Super Bowls and been MVP in 4 of them. He is a 13 time Pro Bowl selection, and has led the league in touchdowns 4 times and is a two time league MVP. His record of 26-9 in the post season is also the highest win total for a QB. To put those 26 postseason wins in perspective, Joe Montana is second with 16, and Brady has more than Terry Bradshaw and Troy Aikman COMBINED. I just don't see anyone else with a total body of work that is that impressive.
Plenty of other great players out there like Jim Brown, Jerry Rice, LT x2..., but none who have accomplished as much as a man named Brady.