While Aetna has committed to retaining a workforce in Lousville as part of their proposed Humana acquisition and I see the continued shift to remote workers with people coming into the office when needed via 'hoteling' arrangements (Accenture has been doing that for years, its also big with the Big 4 accounting firms now and even JP Morgan is jumping on that train in NYC), I can't see them moving their headquarters, especially to Boston. Boston has a strengths in education, health sciences, investments, and high tech; but, not health insurance. There are 3 health insurers in Boston, all are midsize and only 1 reaches outside of the Boston market (Harvard Pilgrim in RI, NH & CT). Thus, they don't have a workforce with experience with large health insurers. Hartford is the HQ or has very large operations centers for each of the truly 'national' health insurers in the US - UHC (Hartford), Anthem/Wellpoint (Wallingford), Aetna (Hartford - HQ), and Cigna (Bloominfield - HQ). That is something that is very hard to ignore.