I just read this thread and a particular incident came to mind in men's college basketball:
By the fall of 1965, UCLA had won two consecutive national championships (1964, 1965). Freshmen couldn't play varsity basketball in those years, but the freshman team could play an exhibition game against the #1 ranked UCLA varsity. Lew Alcindor had 31 points and 21 rebounds to lead the freshman team of Lynn Shackleford, Kenny Heitz, Lucius Allen, and Kent Taylor to defeat the varsity 75-60. UCLA would not win the championship in 1966, but would win the next seven.
Kareem Abdul-Jabbar comes to mind when I think of a generational college basketball player.