We like Carmellina's the best out of the pasta factories on Hanover.
We live by Il Molo on the back side of the north end. It gets stellar reviews. Went there 2 nights ago for my bday dinner and was not overly impressed.
When I lived in Back Back I liked La Voile over there.
Really depends what you're looking for. For ultra fancy, I had my best meal ever at Ken Oringer's Clio, but then he turned it into a sushi place.
My wife and I are expecting soon, so I'm generally out of the loop now as we don't eat out much.
I can second HK for high end comfort food when I lived in Davis Sq years ago.