1. The poll rankings do not determine the selection committee's rankings. The committee will rank the teams using their own criteria, which do not include the polls.
2. In a true S-curve bracket, the #1 and #8 overall seeds would meet in the Elite 8, but other circumstances (e.g. conference affiliation) can force a deviation from the true S-curve. (For example, if SC is #1 and LSU is #8 per the committee's ranking, they cannot be placed in the same quarter of the bracket.)
3. As for the projected Final Four pairings, the committee's #1 would always face #4, and #2 would face #3.