I always consider that the New England games are almost must wins. In that it does not help that much to win them, but it really hurts when you lose them. Not sure if that makes sense.
It makes some sense, even though it is really hard to win all the New England games no matter how good you are. Usually the New England teams are not all that solid with their RPI ratings, and some are sub 200 in the RPI. Losing to one of those teams can do some damage to your own RPI. However, not all New England teams rate poorly. For example, Rhode Island currently has an RPI of 42, and UConn plays them twice.