Certainly not 50 years and 10 seems highly unlikely as well. What is left of the ACC would be something like one of these scenarios:
A) if it loses just 4 schools: BC, Syracuse, Pitt, Louisville, Duke, California, Stanford, SMU, Wake Forest, VA Tech, NC State, Virginia, GA Tech. So, backfill candidates would include UConn, USF, Memphis, Tulane. Not bad at all. Definitely wouldn't receive current ACC tv revenue but far better than our current situation.
B) if it loses 8 schools: BC, Syracuse, Pitt, Duke, California, Stanford, SMU, Wake Forest, NC State. So, backfill candidates would include UConn, USF, Memphis, Tulane, ECU, James Madison and maybe a couple more but maybe not so as to not super-dilute the tv valuation. Still better than our current situation but not as robust as scenario A, obviously.
C) if it also in addition to scenario B loses Cal and Stanford back to the rebuilt Pac, then it gets even more desperate. I don't think Cal and Stanford want the bedfellows of a rebuilt Pac but it can't be ruled out entirely.
Maybe Notre Dame hangs for a while if it's A, but likely not as they'd reluctantly go to the Big10 given the pressure they'd be under from a football perspective to keep pace on the revenue and football scheduling aspects. Either way, they don't provide a ton of value for their Olympic sports.
What seems pretty certain is UConn's future is better in a remnant ACC than a Big East/FB independent situation.
The next few years are yet another crossroad for the UConn Athletic Department.