When you want your AD to fire a coach, be careful what you wish for. Brad Stevens is the one guy who everyone would call if they were looking to replace a HC, but even then, there's no guarantee he'd thrive in any given environment. Most successful coaches represent a marriage of coaching ability and circumstances. Tom Izzo, Jim Calhoun, Coach K- those guys don't grow on trees, and who knows whether they'd have been as successful elsewhere.
Louisville might be better off without Pitino. I'd be willing to bet they wouldn't be, however.