So there is 1 example of where it has negatively affected the Huskies vs. 3 times where it has benefited them.
The last 5 straight years the NCAA has selected a regional site within 2 hours of UCONN's campus. In 8 of the last 9, there has been one within 4 hours. UCONN has (deservedly) hosted there all 8 times.
Compare that to Notre Dame who earned 8 straight #1 seeds from 2012 to 2019. The only times they got to play within 4 hours of home were in 2014 and 2019. Every other time, as a 1 seed, there was no home regional for them. During the same stretch, UCONN had the luxury of playing close to home for 7 of the 8 years. No one else has had the fortune of consistently being able to play in front of home crowds en route to a Final Four year after year like the Huskies have, so to play the 'victim of the NCAA' card just isn't accurate. At all.
And the TBA Final Four was literally 30 years ago when Final Fours were commonly played on home courts, and Tennessee didn't even make it to the Final Four that year. If you want to go the Tennessee route:
-Tennessee had to play USC in LA for a title in 84
-Tennessee didn't get the Chattanooga regional (2 hours from Knoxville) as a 1 seed in 2005, it went to LSU, who they just beat in the SEC Tournament and is 8 hours from Baton Rouge
-in 2006 UT arguably should've been the 4th #1 at at worst the top #2, but was put in #1 overall UNC's bracket, with regionals in North Carolina
-in 2007, as a 1 seed, Tennessee was forced to played at Pittsburgh in the 2nd round in 2007