You might want to look at the
538 article referenced on this forum, which contains a graph showing the offensive and defensive efficiency of each of the tournament teams. Surprisingly, UConn's defensive efficiency in that graph looks better than their offensive efficiency this year.
Mississippi State has a place of honor on that graph, but not where you might expect. Its offensive efficiency exceeds UConn's and Notre Dame's, and is second only to Oregon. However, its defensive efficiency is below both UConn's and Baylor's -- Baylor is the most defensively efficient team in the tournament by a significant margin, according to the graph. The Bulldogs are only slightly better defensively than Notre Dame, which is not too much of a compliment.
Of course, the input to this graph is influenced by strength of schedule, and (IMHO) it's pretty obvious that because of the strength of their conferences, ND and Oregon have played tougher overall schedules than UConn, Baylor, and Mississippi State. So ND is perhaps shown unfavorably on this graph in comparison to the latter three schools. Oregon's top offensive efficiency score is magnified by the strength of the PAC-12 conference against which they earned those numbers.
The graph suggests that UConn should make quick work of Louisville if they should meet in the Elite Eight. But of course, that conclusion is distorted by the effect of competition (ACC vs. AAC) on the statistics of both teams.