I would say yes. As of right now Duke has a 0.52 WAB lead, 8.82 to UConn's 8.29. Duke losing to Michigan is not going to cost them a lot of WAB points. For example, the Duke's neutral site loss to Texas Tech was -0.25 so let's say the loss to Michigan is only -0.15.
UConn beating Creighton is not going to gain many WAB points. My guess is about 0.20. But beating Villanova on the road will give UConn a decent amount of WAB points. The prior win over Villanova at home was worth 0.45. The road wins over middling and bad BE teams such as Georgetown, Butler, Xavier, PC, etc. were all worth around 0.50 WAB. So I'd say the win at Villanova would be worth about 0.65.
So 0.65 plus 0.20 is 0.85, which would put UConn at 9.14. Duke would go from 8.82 to 8.67.
Does all this make sense?