It's a fair question. Say, if you have like 100 at +2400 on UConn to win the championship, and we're up against NC State +13.5 with a moneyline of -1000/+700 or whatever, do you:
A) Bet 1100 on NC State +13.5 at -110 (+1300 if UConn wins huge, +3400 if UConn wins small, +900 if NC State wins)
B) Bet 300 on NC State ML +700 (+2100 if UConn wins, +2000 if NC State wins)
I can see arguments either way, though I'd personally be inclined to go with B to lock in the bigger payout even though it eliminates the chances of a jackpot.