The director has proven to be capable enough with action films, hopefully he can improve a little in that regard. I thought his Kong flick was only ok, but still pretty watchable. He certainly seems to feel strongly about the MGS property.
I like very much the idea about Oscar Isaac but I guess they would make Solid Snake a little younger, most likely an origin story.
I get a bad feeling though that they’ll feel the need to make some of the characters more “hollywood”. Revolver Ocelot, Psycho Mantis, Liquid Snake, Big Boss, etc. can’t imagine them using some of the screwier names Kojima came up with.