The final score will depend on how quickly DePaul can get back on defense after a missed shot. Since they take a lot of threes there will likely be a lot of long rebounds so that could slow down the UConn break. I also suspect that if UConn develops a significant lead Geno might want to slow things down and work on half court offense for the Baylor game. Of course, I could also be talking through my hat.
In any case, I think UConn wins handily with a MOV of 31 at 93 to 62.
As an aside, a lot of posters say that the Huskies need to defend better on the perimeter and while I haven't looked up stats, I don't think any team we have faced has shot at or above their team percentages on threes (or twos for that matter) yet. I know, it's very early for that sort of stat to mean much.