At this point in the season; my prediction for #1 seeds are:
UConn
ND (host school)
Stanford (host school)
Duke/Maryland
That leaves UConn at Louisville or Nebraska and the other ACC team at the other location. I think the committee will take some 'unusual' things into account this time; even if Louisville is closest, I think UConn will be sent to Nebraska and the other #1 seed will be sent to Louisville.
Based on how the rest of the season goes, if ND enters the tournament undefeated or with only 1 'good' loss (most likely loss in this scenario is either at Maryland or at Duke), they will be the #2 1 Seed. If ND enters with 1 regular season loss AND lost in the ACC Tournament (a possibility), they will be the 3rd or 4th 1 seed, and Stanford will be the 2nd, and the ACC Tournament winner will be the 3rd/4th 1 seed.
If either Duke or Maryland win the ACC battle (regular season and/or tournament) they will be the #3 1 seed and ND will end up bumped to 4th (this is predicated on Stanford not losing another game this season).
I have to imagine, at this point, that if 2 teams can make it out of the ACC relatively unscathed (no in conference losses or only losses to each other after splitting their match ups), they will both be 1 seeds.
Long shots at this point:
Big 12 Winner: whether thats OK State, WVU, or Baylor. But, I think even if one of the three goes through the conference play and tournament with only 1 loss, I think the ACC is still a stronger conference and the winner or top 2 teams coming out will be 1 seeds.
Louisville: ACC has a stronger conference, so I imagine if Duke only has losses to UConn and ND, they will be picked over Louisville. However, if Duke and Maryland beat each other up, lose to Notre Dame each time they met, and have another loss or two in conference, AND Louisville only has the Kentucky loss and losses to only UConn, THEN I can see Louisville moving in as the 4th #1 seed.
North Carolina: unless they put together some kind of magical run through the ACC, but I think the conference is too top heavy for a lower tiered team to knock out all three favorites and win both the regular season and tournament
Baylor: hit a rough patch last week against Kansas, so they may be officially out of the running for a 1 seed