Exciting potential matchups at first glance:
SC Regional:
Iowa-Iowa State in the Sweet 16. Interstate rival game, Iowa won last year, Iowa State won this year. Clark vs. Joens. Should be a really fun game to watch if both advance.
Iowa-SC in the Elite 8. The two heavy favorites for NPOY will battle it out if they meet.
Louisville Regional:
Tennessee-Oregon in the 2nd Round. Tennessee is struggling but still showing some fight/grit. Oregon has been so hot and cold this year. Guessing it'll be a tight game.
Baylor-Ole Miss in the 2nd Round. I could see Ole Miss giving Baylor some trouble if Egbo gets into foul trouble. Also 2 very good forwards going head to head in Austin/Smith.
Baylor-Michigan in the Sweet 16. They had an epic battle in last year's Sweet 16, they're lined up for a rematch in this one.
Louisvlile-Baylor in the Elite 8. Both were in contention for last #1 seed and I think it'll be a good battle.
Stanford Regional:
Maryland-Virginia Tech in 2nd Round. Maryland has been very streaky this year, Va Tech hasn't pulled off any big upsets this year but has played good teams tough. I could see Va Tech pulling the upset.
LSU-Ohio State in the 2nd Round. Both teams have sensational backcourts, I think it'll be a hotly contested game.
LSU-Texas in Sweet 16. Kim vs. Vic at their new schools. Both teams have greatly overachieved relative to the amount of talent on their roster.
NC State Regional:
Notre Dame-Oklahoma in the 2nd Round. Both teams have been trending down as of late, one will likely make their way to the Sweet 16. Both have strong backcourts and shooters.
Indiana-Kentucky in the 2nd Round. Probably the most intriguing potential 2nd round matchup. Indiana blew out Kentucky the first game but Kentucky is red hot and playing very good basketball.
UCONN-NC State in the Elite 8. NC State is a tough matchup for UCONN IMO since they're just solid at every position even though I wouldn't consider them elite at any spot. Should they meet, UCONN will be playing in front of a huge home crowd which gives them a boost, and everyone appears to be healthy just in time for the NCAAs. I could see this being a phenomenal game.