Spoken from someone who did a lot of traveling during the college athletic career I suppose? NOT! That's what I like about this board, so many well informed because they lived views and have lots of compassion.
Familiar surroundings, normal routines, friends and ability to be by yourself are what makes people successful, athletes included. I have done both college athletic trips and business trips (both when I was young and now that I am older) and YES, they are taxing on the mind more so than the body but taxing on both.
These are not normal routines by any stretch and add in the time zone changes, eegads...