All depends what you are looking for.
Best NY slice is NY Pizza Suprema.
Turntable chicken jazz is a good spot as someone previously mentioned (double fried korean chicken)
Keens Steakhouse for a mutton chop if you are looking to spend $$$ for goooood food.
Refinery Rooftop if you are a 20 something looking to party with someone bougie people.
Barcade if you are a nerd and want to play old school arcarde games.
Hooters if you are looking for... well you know.
Don Angie is decent walk to West Vill but is awesome for modern italian american cuisine.
You can pretty much do anything you want to do, be a little more specific with what you are looking for and we can try to help you out.