With respect, I feel like this analysis is really short on facts, and its claims don't actually fit the data. Here's the data for the past 5 tournaments:
In 2015, no PAC-12 teams made the Final Four. #4 Stanford was the auto-bid and was sent to Kentucky, #3 Oregon State was the only PAC-12 team to be in the West region (Spokane) and was rewarded with a second-round game against a dangerous #11 Gonzaga that upset them.
In 2016, #7 Washington got to the Final Four by beating #4 Stanford in Kentucky. #2 auto-bid Oregon State was rewarded for its conference title by having to upset #1 Baylor IN TEXAS to get to the Final Four.
In 2017, Autobid #2 Stanford upset #1 Notre Dame in Kentucky, a state which borders Indiana...
In 2018, no PAC-12 made the Final Four. 2/3 Elite Eight teams (#3 UCLA and #6 Oregon State) got there by upsetting higher ranked teams back East (UCLA beat #2 Texas in Missouri, one state over from Texas, and Oregon State beat Baylor in Kentucky).
In 2019, #2 Stanford was the auto-bid and was reward with a trip to Chicago against #1 Notre Dame (very close to a home game for the Domers). #2 Oregon got to stay in the Portland regional. That's probably the only game in all five season where region significantly benefited a PAC-12 team in an unfair way (i.e., the lower seeded PAC-12 benefited from geography - and even there, I think most people thought Oregon was a better team than MSU and they only ended up #2 because Stanford edged them in the PAC-12 championship game).
I don't know what year you have in mind, but the last time this happened Stanford was the auto-bid and a #1 seed with a 31-1 record and Duke was a #2 at-large that went 24-5. I'm pretty sure Stanford deserved the West #1 seed over Duke. If you're remembering a different year before 2012, then you're talking about the PAC-10 era, and therefore not the era any of the rest of us is talking about, which is the past 5-6 seasons.