Changes have already been taking place over the past 20-30 years. Notice the SEC has been doing better than the B1G. More people used to live in the Midwest due to the manufacturing jobs. The Bos-Wash megalopolis looks fine for a while. Richest area in the country. NYC is still the largest city in the country and is the financial hub.The changes you are talking about will take 20-30 years to have full effect. And that's if it happens as dramatically as you seem to be suggesting.
Also, Connecticut is shrinking relative to other states, so if population and demographics are all that matters, we're screwed no matter what.