I watched them live on South Carolina-Louisville, then watched main broadcast for both UConn games and would go back and watch recording of Sue and Diana. I loved it.
I'm also a big fan of the Manningcast but one obvious difference is going to be that in football they have 30 to 45 seconds after each play to analyze it, so there is going to be more straightforward game talk. If Sue and Diana start talking about a pick and roll and then compare it to one they ran in 2002 and then explain how Geno screamed at them in a key moment of some game when they failed to execute...well, that's a great story. But in the meantime, six more plays have happened in the game. It's impossible for them to analyze too much with the play-by-play given the nature of the game.
What they do share in common with the Mannings is that chemistry and shared history. After the Mannings debuted you saw stories from, say, NBA people dreaming of having something similar. Again, you'd have similar issue with the speed of the game, but the main thing is finding two people like Peyton and Eli. Who are you getting? The Plumlee Bros? But with Sue and Diana you do have two people with incomparable history together who are also extremely entertaining and fun to listen to while having great chemistry.
There could be smoother aspects but overall I thought it was a great addition and hopefully becomes a mainstay.