Due to all the upsets of top seeds in the low major conference tournaments the 13-16 seeds are quite weak this year. The 1s and 4s are quite strong as well.
I don't anticipate a lot of huge crazy seed upsets compared to the last few years. Most upsets will probably come from the 9-12 range. 11s over 6s seem particularly good. I might be buying the NC state train. Winning 5 in 5 has in the past led to good NCAA tourny results.
This.
The flip side of bubble teams being left out is that the 11-13 lines are much, much weaker than usual (except for New Mexico, who should have been a 9 and got screwed like the rest of the MWC). The 14-16 lines are about the same, actually.
I expect very few first round upsets but potentially a number of second round upsets. After the first 3 teams (us, Houston, Purdue) and the next 4 (UNC, Tennessee, Arizona, ISU), there's actually not a lot of separation between the #3 seeds and the #7 seeds.
I wouldn't be surprised to see a lot of brackets with Sweet 16s like 1-4-6-7.