Agree with those above - the tournament for a top two seed line team, is really three warm-up games, and three tough games. If you can't get out of the sweet sixteen game easily, then you weren't going to win anything anyway, however wacky the committee has put together the brackets. If you are scared of the 13-20 ranked teams (4 and 5 seeds) who are most likely to be the S16 opponent for a 1 seed than you don't belong as a 1 seed. If a two seed is worried about the 9-12 or 21-24 seeds then they don't have a chance against in the E8.
And so forget everyone else in the bracket - look at those three games in 'chalk' and they are going to be tough in every bracket. Louisville may have a lesser resume than NC St, but that is a very experienced squad with a very dangerous coach who has a history of messing up brackets in the tournament and beating 1 seeds. (Hello Baylor Prof!) Baylor, TA&M and Maryland all look plenty dangerous. And none of the 1 seeds have unblemished records.
I think the committee had an easy job at the top of the brackets - 8 teams separated from the rest and none of them really separated from each other this year. If we had Uconn/Baylor and Uconn/Louisville specifically, and a bunch of other meaningful OOC games we would have a lot more information and maybe some more separation. If any of the Pac had played a serious OOC we would have more information. But none of that happened and we have what we have. A bunch of teams with very little in the way of common meaningful opponents in a fractured season.
The biggest issues I think people have with the brackets is further down the seeding. Not hearing anyone clamor that some 3 seed should have jumped into the two seed line, or that some 5 seed should have been a 4 seed. And with no 'home games' and no regional bias, there isn't a lot else to complain about.