Honestly as I get older both two knobs and one handle are becoming problematic. My biggest gripe are the faucets themselves that are so short you keep brushing your hand against the back of the sink while you're lathering up. I like faucets that extend well out and up high into the sink.
But let's not get into the poor bathroom habits of most men. As a NY-er I use a lot of public restrooms and BOY-O, are guys filthy, skulking, nosey lurkers. Few (maybe 6 out of 10) wash their hands after using the toilet and even less (1 out of 10) practice proper hand washing techniques. As someone who worked in the health field for 25 years I was required to be instructed any number of times on proper hand washing, with and without ultraviolet light demonstrations. As a rule I try to never shake hand with guys. I fist bump or nod and smile.