Did Louisville get "screwed" as a three seed? Likely.
Did Louisville getting the three seed and not having to have UConn and Notre Dame in its Regional turn out better? Absolutely.
Did Stanford get "screwed" as a two seed? Probably, based on the resume, especially in the non-conference.
Did Stanford get "screwed" by having to go to Ames, Iowa for a second round game, potentially facing Iowa State (believe on its home floor)? Definitely.
Did Stanford getting the two seed, not having to play UConn and Notre Dame in its Regional, and getting to host South Carolina, the most vulnerable of the four top seeds, on its home floor turn out better? Absolutely.
Did South Carolina have the resume for a #1 seed? Maybe.
Was there another team more deserving of a #1 seed? Probably.
Did South Carolina benefit from getting the #1 seed by having to travel three time zones away for all of its games, playing in Seattle, Washington and Palo Alto, California (Maples Pavilion, no less)? Absolutely not.