I see them putting Pack on Newton and play him tight, Wong on Hawk to start and switch with Poplar or Miller as well.
They basically play a 4 guard line up. Now who do put Karaban on Miller? I fear AK might see early foul trouble.
That makes the most sense to me for them defensively.
I will say this, I think they are poor defensively partially by design. They are like Creighton in that they only really have five guys who scare you, their starters. The main difference is they don't have an eraser in the middle. They do go eight, but 6-8 aren't near the players 1-5 are (good, serviceable but not near the starters). They can't afford foul trouble. I think it's one of the reasons you have seen them go on late runs. They start playing harder defense as the game winds down, while still making tough shots. I am not saying they are world-beaters defensively but I do think they have a second gear they don't usually exert until the end of games.
Sanogo is going to have his hands full with Omier to start. He is a load. Not that he will back Sanogo down, but it will be hard for Sanogo to back him down also. Sanogo should be able to shoot over him but getting close shots might be hard. Depends on how the refs call things. I don't think they double the post at first and rely on Omier being strong enough and having a lower center of gravity to keep Sanogo a step or two outside of his kill zone.
Personally, if they can stay out of foul trouble and commit fully to defense I would put Pack on Newton and Poplar on Jackson and pressure both. I want to take away Jackson's passing sight lines as much as possible and make Newton pick up his dribble. Letting Jackson stand at the top of the key with no-one around waiting for a man to cut, or a screen to be set and a man to get open is a recipe for disaster for other teams unless your off the ball defense is top notch.
Wong is fast and athletic enough to stay on Hawkins around screens but I have yet to see him commit to defense for more than 10 minutes a game.