When Izzy went down and wailed in agony, it reminded me of KML in the first Stanford game. Thankfully, for KML, it was the arm, a recoverable appendage. However, I knew immediately Izzy had a leg injury that was probably the end of college. Whether it was an ACL or a micro fracture, it wasn't going to be good for her, her team, or the myriad folks who cheer for the same.
All you can do on Rocky Top is wish her the best and thank her for what she's given to the LV program. After all, the feeling of loss only speaks to the magnitude of what her contributions have been.
I'm not a praying man, but the LV faithful have my sympathy.