I’m more concerned about winning the first game than the second, no matter which region or seed we end up in

Any hypothetical first round NCAAT game for UConn is basically a 50-50 chance of winning it. As far as the first round games go, there really isn't much difference between 6 vs 11, 7 vs 10, and 8 vs 9, all those are pretty much 50-50 propositions to win give or take some depending on the match ups.
Let UConn beat Georgetown convincingly.