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Message: [QUOTE="Shine33, post: 3275596, member: 10026"] A decrease in neuron and skeletal muscle mitochondrial function is observed in a number of disease and injury states including CNS trauma, neurodegenerative disease, type II diabetes and obesity[1-3]. H “However, indirect evidence of mitochondrial function using near-infrared resonance spectroscopy to measure tissue oxygenation revealed that muscle oxidative capacity was decreased 50%-60% in participants with SCI 2.7-22 years after injury compared to AB controls[53].” I linked the study above in a reply to PJ. Anyway, I’m not here to flex my brain muscle, you guys seem to have a lot of knowledge so I don’t want to act like I know stuff you don’t. I may be misunderstanding something about cellular function bc I’m weak there but my logic is spinal cord injury affects nerve transmission to peripheral systems which ultimately affects Cell function down the line. Simple but makes sense to me... is my line of thinking off base? [/QUOTE]