OT: - Coronavirus Good News maybe | Page 2 | The Boneyard

OT: Coronavirus Good News maybe

My wife is a nurse and will have her second shot next week. I’m a teacher and eagerly waiting the news of when I can get mine. Rumor is late January.
Weird. I'll be working on my second one in a couple of hours.

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I hate it in late March, my wife never caught it and we shared a kitchen, bathroom, etc for 4 days before I realized I just wasn’t “worn down” and got sick. Both had antibody tests in early May (one month post illness recovery for me) and I had them and she didn’t.
 
Yep, can't draw conclusions from small anecdotal sample sizes/experiences.

This is what's most important to look atwrt vaccine effectiveness (from the actual placebo-controlled trials of the 2 mRNA vaccines). I can tell you that these are the 2 most beautiful graphs I have seen in 20+ years as an infectious diseases healthcare professional. I have no reason to believe that the efficacy won't be very similar "in real life".

Pfizer/BioNTech vaccine:

View attachment 63338


Moderna Vaccine:

View attachment 63339
I agree. As a toxicologist for Merck I worked on a number of their vaccines over the years and the efficacy (and safety) for both Pfizer and Moderna is on the order of some of our best vaccines in the world. I am a little worried about the AstraZeneca vaccine though as they need to look into that odd dose response they saw. Its being promoted heavily because of reduced storage requirements but efficacy was only 70% at full double dose, but higher when the first dose was a half dose? We should see J&Js single dose vaccine data by the end of January and possible an EUA shortly thereafter. Folks if you are wondering whether to take the vaccine or not - please take it. While the development and approval of a vaccine like this in under a year is the equivalent of UCONN beating Duke in the NCAA Finals, I am confident that it is safe and effective. I am 69 and waiting patiently for my shot down here in FL
 
That is because the first dose makes you about 60% immune to the virus while the 2nd shot pushes it to as high as 95% which means you could still get it but very unlikely and supposedly less severe.
When you consider that the 2019-2020 flu shot was about 45% effective, those are unbelievably solid numbers.
 
I agree. As a toxicologist for Merck I worked on a number of their vaccines over the years and the efficacy (and safety) for both Pfizer and Moderna is on the order of some of our best vaccines in the world. I am a little worried about the AstraZeneca vaccine though as they need to look into that odd dose response they saw. Its being promoted heavily because of reduced storage requirements but efficacy was only 70% at full double dose, but higher when the first dose was a half dose? We should see J&Js single dose vaccine data by the end of January and possible an EUA shortly thereafter. Folks if you are wondering whether to take the vaccine or not - please take it. While the development and approval of a vaccine like this in under a year is the equivalent of UCONN beating Duke in the NCAA Finals, I am confident that it is safe and effective. I am 69 and waiting patiently for my shot down here in FL

Picking d o o k against UConn in '99 was such a suckers bet.

I said it then and I'll say it now. UConn wins that game 7 out of 10 times. Maybe 8 out of ten.
 
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When you consider that the 2019-2020 flu shot was about 45% effective, those are unbelievably solid numbers.
Yeah its pretty unbelievable. I was excited when i heard 65-70% but 95% is just amazing. If those numbers hold and 70% of the world gets vaccinated we could see covid go the way of the dodo. Lets hope this is the case.
 
My partner works in healthcare and received the first shot the week it came out. One of her associates got the shot on the same day and last week both her husband and toddler tested positive while she has remained negative. Hubby is still very sick. Anecdotal but still...
Great, just don't read about the South African variant.

For those spouses not contracting it, are they O+?
 
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Great, just don't read about the South African variant.

For those spouses not contracting it, are they O+?

My wife tested positive on Sunday and is O- type. Both my kids tested positive as well, they were the known exposure, yet I the one with A+ blood has stayed negative.
 
Just got the Moderna shot, first dose, completely psyched and surprised it was available. Other than soreness at the injection site, no side effects thus far. I thought I might have had a fever, but it was likely from sweating while wearing a snow hat during a run :)
 
Personally, I support giving as many people the first dose as possible to give as many people some level of immunity while production ramps up and until the J&J vaccine comes on-line.
 
I tried to go to Chat, but it appears it is not working so I will do this on the BY forum. I am over 70 but not 75, and live in CT so when is it likely the vaccine will be available for my age group?

Thank you for your posting.

This is a great thing that we have all kinds of experts on the BY.


 
Great, just don't read about the South African variant.

For those spouses not contracting it, are they O+?
The wife just told me early tests show the pfizer vaccine may be effective against the SA variant. That's good news.
 
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Chief is a graph/Big Data guy. Very impressive. The fly in the ointment may be the South African strain, hopefully the vaccines will work well with that too but the crowns are significantly different. In the meantime, support your immune system!
 
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I agree. As a toxicologist for Merck I worked on a number of their vaccines over the years and the efficacy (and safety) for both Pfizer and Moderna is on the order of some of our best vaccines in the world. I am a little worried about the AstraZeneca vaccine though as they need to look into that odd dose response they saw. Its being promoted heavily because of reduced storage requirements but efficacy was only 70% at full double dose, but higher when the first dose was a half dose? We should see J&Js single dose vaccine data by the end of January and possible an EUA shortly thereafter. Folks if you are wondering whether to take the vaccine or not - please take it. While the development and approval of a vaccine like this in under a year is the equivalent of UCONN beating Duke in the NCAA Finals, I am confident that it is safe and effective. I am 69 and waiting patiently for my shot down here in FL
I have a friend connected with John Hopkins and the Gates Foundation. They are excited about the Johnson and Johnson vaccine. The Pfizer and Moderna vaccines focused on the crown RNA messenger. It’s probably good to have vaccines with different approaches, if mutations over time fundamentally change an aspect of the virus.
 
The wife just told me early tests show the pfizer vaccine may be effective against the SA variant. That's good news.

UK B.1.1.7 variant as well per their reports. That was expected.
 
Wife is getting second shot on Tuesday and I’m part of plan 1B and we haven’t been given a date just yet. We should hear more today or next week.
 
I think I'll be somewhere in a 1C or 2A type grouping. I'm expecting some time in February to be able to sign up for the vaccination.

I'm not personally "worried" but I am watching with interest at low levels of vaccinations by staff at working home, first responders such as EMTs and firemen, and medical staff at hospitals and health care facilities.

These are the people who have had the most exposure, including dealing with asymptomatic and pre-symptomatic and they're not rushing to get the vaccination right away. And from what I've read anecdotally, this is across the country, not just specific regions.

I'm glad to see adverse affects have been few and far between for those who have been vaccinated.
 
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A good summary here of COVID and its impact on the body. Scary stuff:

 
I think I'll be somewhere in a 1C or 2A type grouping. I'm expecting some time in February to be able to sign up for the vaccination.

I'm not personally "worried" but I am watching with interest at low levels of vaccinations by staff at working home, first responders such as EMTs and firemen, and medical staff at hospitals and health care facilities.

These are the people who have had the most exposure, including dealing with asymptomatic and pre-symptomatic and they're not rushing to get the vaccination right away. And from what I've read anecdotally, this is across the country, not just specific regions.

I'm glad to see adverse affects have been few and far between for those who have been vaccinated.
Vaccines were being administered nonstop at the hospital I was at this morning. They looked like they can do 10-20 an hour per person and they had three people vaccinating. Seemed like a pretty strong turnout, but anecdotal of course.
 
So my SO had her 2nd shot yesterday and has her card. I'm thinking if I can get on the list soon we can get some great travel deals!
 
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