It's hard to tell the net impact. Did Wednesday suck for UConn and Pitt? Sure, but they probably got a higher than average number because there was little else to bet on and there weren't 10 other games on. Almost all the announcers suck - so it's not like that drives anything.
The Big East will put up much lower numbers on cable NBC in the short term. I don't even see how it could be debated. What the Big East has averaged in the past is a HUGE number on NBCS. They had a SDSU/ basketball game draw 19k viewers.
You play on Saturday you compete with ABC, CBS, CBS cable, Fox Regional, ESPN, ESPNU, ESPN 2, BTN, Pac 12 net and there are millions of college football fans who are at games.
MACtion is a concept because they play on Tuesday and Wednesday. If they played on TV on Saturday it would mean nothing.
I saw an article today that proposed tht more than half of Sunday ticket subscriptions are driven by gambling. Having that community captive drives television ratings a lot.