The issue with P5 conferences is not their RPI which is pretty meaningless to conference champions, it is the strength of the top 4 teams in the conference because those are the only ones that should give a #1 or #2 seeded team a true test. On that basis this year:
ACC is far and away the top conference with all likely to be top 16 teams in the tournament and the 5th team
Miami just on the outside though Massey has them at #16 (as does the coaches poll)
Number 2 is pretty clearly Pac12 with three teams likely to host even if the top team is somewhat flawed in terms of record. The fourth team is UCLA somewhere around 20th.
#3 and #4 - the Big12/SEC are weak third/fourth with Baylor a clear #1 and Iowa St somewhere in the mid teens and hosting, followed by Texas clinging in the top 25 and Kansas St somewhere around 30. (Neither team should really provide a challenge to Baylor and they didn't) And the SEC with SCar which should not host but probably will in the late teens and TX Am and Kentucky also hanging in the same area.
#5 is Big10 here because the best teams are Maryland and Iowa both outside the top ten and hosting but followed by Rutgers in the mid twenties and the Mischigan in the 30s.
(I drop the SEC behind the Big12 because MissSt, Kentucky, and Texas A&M played pretty awful schedules even compared to the BIG12 top 4.)
In terms of #1 Seeds, I would likely give Louisville the 4th #1 seed - I would not penalize them for losing twice to ND, just like the committee used to discount the ND/Uconn loses when they were playing three times a year while beating all other comers. They would probably be just as happy to have MissST get the last #1 in Portland OR and take their chances as the #2 in Albany.
For Uconn, I do not think it makes a difference - one or two in Albany is basically the same and the committee will not move them away. Just as ND or Louisville was slated to Chicago and Oregon or Stanford were going to be in Portland.