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UConn Unaffected by Seton Hall Covid Pause [merged]
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[QUOTE="DocStressor, post: 3775947, member: 10851"] I sense a teachable moment here. Both the Pfizer/BioNTech and Moderna vaccines do prevent the disease with greater than 90% efficacy. COVID-19 is the term for the disease, not the virus that causes the infection (SARS-CoV-2). The symptoms of the disease are largely the result of a strong autoimmune response where the immune system attacks healthy tissue as well as virally infected cells. In 20-40% of people who become infected by the virus, there are no symptoms and thus no disease. In these cases, the viral infection is arrested in the upper respiratory system before a systematic response occurs. It is clear that unvaccinated people who are asymptomatic can spread the virus to others even if they themselves never develop the disease. It is not yet clear yet whether either vaccine can reduce infection or asymptomatic transmission by vaccine recipients. That being said, Moderna recently provided an addendum to their EUA application to the FDA containing additional data that includes asymptomatic cases that occurred in the vaccine and placebo groups during the 28 day period between the first and second shot. It showed a 63% reduction in asymptomatic cases in the vaccine group. The efficacy of the vaccine in reducing asymptomatic viral infection after the second dose has not yet been reported. The same data has been requested from Pfizer and they are supposed to report their results in January. So stay tuned. [URL='https://www.fda.gov/media/144453/download']Moderna Supplementary Data[/URL] [/QUOTE]
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