This is pretty cool to read about. Lots of cool things going on at UConn these days: UConn Researchers Kill MRSA with Tailored Chemistry - UConn Today UConn medicinal chemists have developed experimental antibiotics that kill MRSA, a common and often deadly bacteria that causes skin, lung, and heart infections. The success is due to their strategy, which found a weakness and exploited it in a way the bacteria should have trouble countering, the researchers report in the Dec. 22 issue of Cell Chemical Biology. Cases of MRSA (Methicillin-Resistant Staphylococcus aureus) are on the rise and increasingly resistant to common antibiotics. The first choice treatment for MRSA, trimethoprim-sulfamethoxazole, is relatively safe and inexpensive. But trimethoprim-resistant MRSA has begun to spread around the globe. Up to 30 percent of infections in sub-Saharan African no longer respond to it, and significant numbers in Europe and Asia as well.