I don't think they will be tired tonight. They all knew they were beat after the game but two days to recover is plenty of time if you focus on the recovery which I am sure they did. Duke played a tenacious defense and so did UConn and that will wear you out if you have a regular bench rotation and UConn basically went with 6 in the game.
Watching USC I noticed they play slow and they don't have a lot of movement on offense. JuJu shoots a lot and misses way more than she makes so if UConn can stay close on rebounds and limit second chance points this should be a game they win. I expect Paige to be at her best and AE has to have a break out game eventually, why not tonight?