I don't know why but this movie makes me think of "ST Vincent". Bill Murray has done the occasional really touching movie over the course of his career. "St Vincent" and "Meatballs" are two that come to mind. Another movie that does not have Bill Murray but in a similar vein is "Cannery Row". A really humorous movie in a sad sort of way. I told someone I found the movie very funny and they said it was hard to think of Steinbeck as funny but after he watched the movie he said it put the story in an entirely different perspective.
I saw St. Vincent during one of my Bill Murray kicks a few years ago. While you don't expect Murray to be quite this ornery, he carries it off. It is well worth seeing.