I watched the game, then read the comments on this forum complaining about the officiating, then watched the game again on replay. I agree with nwhoopfan that several of the 4th quarter drives to the hoop on which UConn scored could (not unreasonably) have been called charges, which would have removed 6 or 8 points from the scoreboard.
On the specific play which was mentioned on which Megan Walker was called for a charge, it is true that the defender started to fall backward before Megan made contact with her. But Megan still did make contact, and the defender had established position, so I think the call was justified.
In general, I think the refs took a "let them play" attitude and mostly refrained from calling borderline charge or block calls. It appeared to me to be consistent at both ends, but since UConn was the more muscular team (not usually the case), it probably benefitted UConn more than DePaul.
I would not blame the refs for the closeness of the score, but it is certainly true that if DePaul had 25 fouls called on them (as happened when they visited Oregon State), the game would not have been nearly as close.