Notre Dame hasn't lost a home game since 2/14/10. Based on that fact alone, it would seem as if doom is in the forecast.
I'll say: doom, gloom, and doom.
Let's keep it a secret that uconn snapped their 45 home game win streak in '09 (they are currently on a 30 game streak).
They are undersized: Cooley is really the only good rebounder on their team, and at just 6'9", AD and AO
should have a big game rebounding.
They are not a very deep team, so if Cooley or Martin get into foul trouble, they'll be in trouble.
As mentioned above, I expect they will play mistake free ball, so uconn has to take the game from them and not play as sloppy as they've been playing to start the big east season. Uconn needs to minimize its turnovers!