I'm surprised that there are only 3 responses tot this thread. Though he did not utter the words himself, Harold Ramis is responsible for the many occurrences of the familiar retort to an easily and unnecessarily offended poster repeated on the Boneyard ("Lighten up, Francis.").
He brought a lot of joy to the lives of anyone in their mid 30's and older. Just look at his list of writing credits: Animal House, Meatballs, Caddyshack, Ghostbusters (I & II), Back to School, Armed and Dangerous, Groundhog Day, and Analyze This (and That): All of them are instant classics. Films don't have to be poignant to be entertaining and if you want to be a well rounded movie viewer, you better have a few of these comedies among the Best Picture nominees every year.
He was even good in his bit parts (Knocked up and As Good as it Gets).